Product
소개
NuGel™ NRicher™ Mx Low Abundance Proteome Enrichment
Enrich low abundance proteomes
• Enriches and normalized low abundance sub-proteomes 5-10X
• Compress proteome concentrations
• Tissue and species agnostic
• Suitable for small volume mg scale preps
• Composite NRicher™ 6 surfaces can be deconstructed and optimized for
biomarker enrichment
• Supports Compound Centric Displacement Proteomics (CCDP) method
BSG has developed a new method for proteome separations based on chemically derived weak affinity or imperfect fit interactions. Without the use of antibodies, progressive displacement allows the beads to bias for or against certain proteins, without compromising protein integrity.
The NuGel™-based NRicher™ products are adaptable to any measurable protein function from any sample type, to aid in the discovery of new biomarkers. They support all functional, activity-probe, chemical and top-down proteomic applications .
주문정보
* Each prep processes approximately 0.5-1.0 mg total protein
관련자료
The Functional & Chemical Proteomics Handbook 03/2016
Oka, Amita R., Matthew P. Kuruc, Ketan M. Gujarathi, and Swapan Roy. " Functional Proteomic Profiling of Phosphodiesterases Using SeraFILE Separations Platform." International Journal of Proteomics 2012 (2012).
New Chemical Proteomic Methods To Access Drug-Protein Interactions
US HUPO 2014. Frontiers in Proteomics: Advancing Biology through Technology and Computation.
NuGel™ PROfessor™ abstract entitled "Compound-Centric Displacement Proteomics - An Advantaged Method To Survey Small Molecule-Protein Interactions" poster board 096 presented at US HUPO 2014