Product
소개
Magic™ Membrane Protein Characterization
Creative Biolabs provides professional custom services in membrane protein characterization to facilitate our customers' research, development, and applications of membrane proteins. Our versatile platform is compatible with various structure, kinetics and function profiling of membrane proteins. This service can be offered separately or as an integral step of our membrane protein preparation package, to ensure that the final product can meet custom standards of purity, function, structure, binding behaviors, etc.
Our membrane protein characterization services including but not limited to:
• Native polyacrylamide gel electrophoresis (PAGE)
• SDS polyacrylamide gel electrophoresis (PAGE)
• Fluorescence spectroscopy
• Circular dichroism spectroscopy
• UV-Vis absorption spectroscopy
• Chemiluminescence
• Radiometry
• Dynamic light scattering (DLS)
• Analytical gel-filtration/size-exclusion chromatography
• Analytical ultracentrifugation
• Western blotting
• Enzyme-linked immunosorbent assay (ELISA)
• Immunoprecipitation
• Surface plasmon resonance (SPR) and bio-layer interferometry (BLI)
• X-ray crystallography of membrane proteins
• Nuclear magnetic resonance (NMR) spectroscopy
• Cryo-electron microscopy (Cryo-EM) of membrane proteins
From these services, our customers can obtain information for membrane protein structure, function, activity as follows:
• Purity and composition
• Topology, size, and oligomeric state
• Atomic structure
• Thermodynamic and kinetic parameters for binding with drugs, antibodies, and ligands
• Thermodynamic and kinetic parameters for folding and oligomerization
• Enzyme activity
• Signal transduction efficiency and selectivity
• Molecule and ion transportation efficiency and selectivity
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